时间:2025-04-03 20:54:09 来源:网络整理编辑:時尚
Scientists are finding more evidence that you should probably cut down on your sugar intake.。 A grou
Scientists are finding more evidence that you should probably cut down on your sugar intake. 。
A group of U.K. researchers say they've spotted the molecular "tipping point" that could explain sugar's ties to Alzheimer's disease. 。
Their findings provide further evidence that there might be a link between high blood sugar levels and the memory-robbing disease, though they don't prove that sugar causes Alzheimer's outright.。
SEE ALSO:Doctors discover why stressed out people have more heart attacks。"Excess sugar is well known to be bad for us when it comes to diabetes and obesity," said Omar Kassaar, a biologist at the University of Bath, in a press release. 。
"But this potential link with Alzheimer's disease is yet another reason that we should be controlling our sugar intake in our diets," he said. 。
Alzheimer's is a progressive, degenerative disease that eventually hinders a person's ability to function. Along the way, the brain steadily erases all the names, faces, places and stories it's stored up over decades. Some people grow paranoid and depressed, or they stop eating and sleeping.。
In the U.S., Alzheimer's is the sixth-leading cause of death.。
With Alzheimer's, abnormal proteins accumulate into plaques and tangle between the brain's nerve cells. This build-up progressively damages the brain and leads to severe cognitive decline.。
Thanks for signing up! 。
Previous research has shown that glucose -- the body's main source of sugar -- and its related breakdown products can damage proteins in the body's cells. This happens through a reaction called glycation: when a sugar molecule bonds to a protein, without the controlling action of an enzyme. 。
But scientists have lacked an understanding of the specific molecular link between glucose and Alzheimer's. That is, until now.。
This week, Kassaar and his colleagues from the University of Bath and King's College London said they've unraveled that link -- a discovery that could lead to new treatments or prevention measures for the brain disease, they said. 。 In the study, which was published Thursday in the journal。In the study, which was published Thursday in the journal。
, the researchers looked at brain samples from people with and without Alzheimer's.。
Left to right: Dr. Rob WIlliams, Dr. Omar Kassar and Prof. Jean van den Elsen in the lab at the University of Bath.Credit: ap commercial photography。
They used a sensitive technique to detect the process of glycation. The researchers saw that, in the early stages of Alzheimer's, glycation damages an enzyme called MIF, or macrophage migration inhibitory factor.。
MIF plays a role in insulin regulation and immune response. By inhibiting and reducing MIF, glycation seemed to hinder the brain cell's response to the accumulation of abnormal proteins.。
The U.K. team found that as Alzheimer's progresses, glycation of the MIF enzymes increases. That makes MIF the likely "tipping point" in disease progression, according to their study. 。
"Normally MIF would be part of the immune response to the build-up of abnormal proteins in the brain," Jean van den Elsen, a co-author and professor in the University of Bath's biology and biochemistry department, said in the press release.。
Featured Video For You。
How Hyperloop One went off the rails2025-04-03 20:02
Best pickleball paddle deals: Shop pickleball equipment sets at Amazon2025-04-03 19:48
John Mulaney's 'Field of Dreams' Oscars bit proves he should've hosted2025-04-03 19:16
Elon Musk confirms X accounts with certain subscriber levels will get Premium bonuses2025-04-03 18:47
Florida hurricane forecast remains uncertain, but trends in state's favor2025-04-03 18:42
YouTube just got more serious about its ad blocker crackdown2025-04-03 18:16
The DOJ is right about the 'green bubbles' in Apple iPhone Messages. Here's why.2025-04-03 18:14
Best health deal: Score the Theragun Pro (4th Gen) for under $3002025-04-03 18:12
This weird squid looks like it has googly eyes, guys2025-04-03 18:12
'Monolith's twisty ending, explained2025-04-03 18:11
Two states took big steps this week to get rid of the tampon tax2025-04-03 20:20
HMD announces a Barbie flip phone2025-04-03 20:18
MSU vs. Mississippi State basketball livestreams: How to watch live2025-04-03 20:15
John Cena has found his post2025-04-03 19:52
Twitter grants everyone access to quality filter for tweet notifications2025-04-03 19:47
2024 solar eclipse: Everything you need to know2025-04-03 18:48
The DOJ is right about the 'green bubbles' in Apple iPhone Messages. Here's why.2025-04-03 18:42
F1 livestream 2024: How to watch F1 for free in US2025-04-03 18:39
Katy Perry talks 'Rise,' her next batch of songs, and how to survive Twitter2025-04-03 18:30
Best headphones deal: $100 off Bose QuietComfort2025-04-03 18:12